PRT062607 - Small Molecule (ID:10406-102)

HMS LINCS ID: 10406-102
Name: PRT062607
Alternative Names: P505-15
LINCS ID:
PubChem CID: 44462758
ChEBI ID:
ChEMBL ID:
Molecular Mass: 393.20
InChi: InChI=1S/C19H23N9O/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(H2,22,25,26,27)/t15-,16+/m0/s1
InChi Key: TXGKRVFSSHPBAJ-JKSUJKDBSA-N
SMILES: C1CC[C@H]([C@H](C1)N)NC2=NC=C(C(=N2)NC3=CC=CC(=C3)N4N=CC=N4)C(=O)N
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
FGR, MAP3K9, PRKACA, PRKCA, ZAP70
2
(equivalent to 100 nM ≤ Kd < 1µM)
FLT3, LCK, LYN, PAK5, SRC, SYK, YES1
3
(equivalent to 1µM ≤ Kd < 10 µM)
JAK2, KCNH2

Batch Information for HMSL10406-102-1:

HMS LINCS Batch ID: 10406-102-1
Provider: MedChem Express
Provider Batch ID: 14151
Salt: 102
Molecular Formula: C19H24ClN9O
Molecular Weight: 429.91
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-08-27
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10406-102-1:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10406-102-1_LCMS.pdf