GW2580 - Small Molecule (ID:10401-101)

HMS LINCS ID: 10401-101
Name: GW2580
Alternative Names:
LINCS ID:
PubChem CID: 11617559
ChEBI ID:
ChEMBL ID:
Molecular Mass: 366.17
InChi: InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)
InChi Key: MYQAUKPBNJWPIE-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
CSF1R, NTRK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
NTRK1, NTRK3
3
(equivalent to 1µM ≤ Kd < 10 µM)
CSNK1A1, DYRK1A, GRK5, MAP4K2, MST1R, ROCK1, TAOK1, TBK1
10
(confirmed non-binding)
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Batch Information for HMSL10401-101-1:

HMS LINCS Batch ID: 10401-101-1
Provider: MedChem Express
Provider Batch ID: 15117
Salt: 101
Molecular Formula: C20H22N4O3
Molecular Weight: 366.41
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-08-27
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10401-101-1:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10401-101-1_LCMS.pdf