Dorsomorphin - Small Molecule (ID:10399-102)
| HMS LINCS ID: |
10399-102
|
| Name: | Dorsomorphin |
| Alternative Names: | Compound C; BML275 |
| LINCS ID: | |
| PubChem CID: | 11524144 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 399.21 |
| InChi: | InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2 |
| InChi Key: | XHBVYDAKJHETMP-UHFFFAOYSA-N |
| SMILES: | C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
BMPR1A, BMPR2, EPHA2, FLT1, FLT3, KDR, LCK, MKNK1, PRKAA1, PRKAA2, PRKAB2, PRKAG1, PRKAG2, PRKAG3, SRC | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | ACVR1, ACVRL1, BMP4, BMPR1B, PRKAB1, RPS6KA1, TGFBR2, YES1 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10399-102-1 | MedChem Express | 11236 |
(Kd <100 nM)