Dorsomorphin - Small Molecule (ID:10399-102)

HMS LINCS ID: 10399-102
Name: Dorsomorphin
Alternative Names: Compound C; BML275
LINCS ID:
PubChem CID: 11524144
ChEBI ID:
ChEMBL ID:
Molecular Mass: 399.21
InChi: InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
InChi Key: XHBVYDAKJHETMP-UHFFFAOYSA-N
SMILES: C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
BMPR1A, BMPR2, EPHA2, FLT1, FLT3, KDR, LCK, MKNK1, PRKAA1, PRKAA2, PRKAB2, PRKAG1, PRKAG2, PRKAG3, SRC
2
(equivalent to 100 nM ≤ Kd < 1µM)
ACVR1, ACVRL1, BMP4, BMPR1B, PRKAB1, RPS6KA1, TGFBR2, YES1
10
(confirmed non-binding)
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Batch Information for HMSL10399-102-1:

HMS LINCS Batch ID: 10399-102-1
Provider: MedChem Express
Provider Batch ID: 11236
Salt: 102
Molecular Formula: C24H27Cl2N5O
Molecular Weight: 472.41
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-08-27
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10399-102-1:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10399-102-1_NMR.pdf,
HMSL10399-102-1_LCMS.pdf