Ribociclib - Small Molecule (ID:10395-101)
| HMS LINCS ID: |
10395-101
|
| Name: | Ribociclib |
| Alternative Names: | LEE011 |
| LINCS ID: | |
| PubChem CID: | 44631912 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 434.25 |
| InChi: | InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28) |
| InChi Key: | RHXHGRAEPCAFML-UHFFFAOYSA-N |
| SMILES: | CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CDK4, CDK6 |
Batch Information for HMSL10395-101-1:
| HMS LINCS Batch ID: | 10395-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 11003 |
| Salt: | 101 |
| Molecular Formula: | C23H30N8O |
| Molecular Weight: | 434.54 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10395-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10395-101-1_LCMS.pdf |
(equivalent to 100 nM ≤ Kd < 1µM)