Abemaciclib - Small Molecule (ID:10390-103)
| HMS LINCS ID: |
10390-103
|
| Name: | Abemaciclib |
| Alternative Names: | LY2835219 |
| LINCS ID: | |
| PubChem CID: | 46220502 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 506.27 |
| InChi: | InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34) |
| InChi Key: | UZWDCWONPYILKI-UHFFFAOYSA-N |
| SMILES: | CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CDK4, CDK6 |
Batch Information for HMSL10390-103-1:
| HMS LINCS Batch ID: | 10390-103-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 0'8492 |
| Salt: | 103 |
| Molecular Formula: | C28H36F2N8O3S |
| Molecular Weight: | 602.7 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10390-103-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10390-103-1_LCMS.pdf |
(equivalent to 100 nM ≤ Kd < 1µM)