XL019 - Small Molecule (ID:10388-101)
| HMS LINCS ID: |
10388-101
|
| Name: | XL019 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 57990869 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 444.23 |
| InChi: | InChI=1S/C25H28N6O2/c32-24(23-2-1-12-26-23)28-19-5-3-18(4-6-19)22-11-13-27-25(30-22)29-20-7-9-21(10-8-20)31-14-16-33-17-15-31/h3-11,13,23,26H,1-2,12,14-17H2,(H,28,32)(H,27,29,30)/t23-/m0/s1 |
| InChi Key: | ISOCDPQFIXDIMS-QHCPKHFHSA-N |
| SMILES: | O=C([C@H]1NCCC1)NC2=CC=C(C3=NC(NC4=CC=C(N5CCOCC5)C=C4)=NC=C3)C=C2 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
JAK2 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | FLT1, FLT3, FLT4, IKBKB, JAK1, JAK3, KDR, KIT, MAP3K9, PDGFRA, PDGFRB, RPS6KB1, TYK2 |
Batch Information for HMSL10388-101-1:
| HMS LINCS Batch ID: | 10388-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 10347 |
| Salt: | 101 |
| Molecular Formula: | C25H28N6O2 |
| Molecular Weight: | 444.53 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10388-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10388-101-1_LCMS.pdf |
(Kd <100 nM)