NMS-1286937 - Small Molecule (ID:10380-101)

HMS LINCS ID: 10380-101
Name: NMS-1286937
Alternative Names: NMS-P937
LINCS ID:
PubChem CID: 49792852
ChEBI ID:
ChEMBL ID:
Molecular Mass: 532.22
InChi: InChI=1S/C24H27F3N8O3/c1-33-6-8-34(9-7-33)15-3-5-18(38-24(25,26)27)17(12-15)30-23-29-13-14-2-4-16-20(22(28)37)32-35(10-11-36)21(16)19(14)31-23/h3,5,12-13,36H,2,4,6-11H2,1H3,(H2,28,37)(H,29,30,31)
InChi Key: QHLVBNKYJGBCQJ-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
PLK1
2
(equivalent to 100 nM ≤ Kd < 1µM)
FLT3, MELK
10
(confirmed non-binding)
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Batch Information for HMSL10380-101-1:

HMS LINCS Batch ID: 10380-101-1
Provider: MedChem Express
Provider Batch ID: 12242
Salt: 101
Molecular Formula: C24H27F3N8O3
Molecular Weight: 532.52
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-08-27
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10380-101-1:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10380-101-1_LCMS.pdf