NMS-1286937 - Small Molecule (ID:10380-101)
| HMS LINCS ID: |
10380-101
|
| Name: | NMS-1286937 |
| Alternative Names: | NMS-P937 |
| LINCS ID: | |
| PubChem CID: | 49792852 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 532.22 |
| InChi: | InChI=1S/C24H27F3N8O3/c1-33-6-8-34(9-7-33)15-3-5-18(38-24(25,26)27)17(12-15)30-23-29-13-14-2-4-16-20(22(28)37)32-35(10-11-36)21(16)19(14)31-23/h3,5,12-13,36H,2,4,6-11H2,1H3,(H2,28,37)(H,29,30,31) |
| InChi Key: | QHLVBNKYJGBCQJ-UHFFFAOYSA-N |
| SMILES: | CN1CCN(CC1)C2=CC(=C(C=C2)OC(F)(F)F)NC3=NC=C4CCC5=C(C4=N3)N(N=C5C(=O)N)CCO |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
PLK1 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | FLT3, MELK |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10380-101-1 | MedChem Express | 12242 |
(Kd <100 nM)