CGP74514A - Small Molecule (ID:10355-101)
| HMS LINCS ID: |
10355-101
|
| Name: | CGP74514A |
| Alternative Names: | |
| LINCS ID: | LSM-6711 |
| PubChem CID: | 9908173 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 385.18 |
| InChi: | InChI=1S/C19H24ClN7/c1-2-27-11-22-16-17(23-13-7-5-6-12(20)10-13)25-19(26-18(16)27)24-15-9-4-3-8-14(15)21/h5-7,10-11,14-15H,2-4,8-9,21H2,1H3,(H2,23,24,25,26)/t14-,15+/m0/s1 |
| InChi Key: | UTBSBSOBZHXMHI-LSDHHAIUSA-N |
| SMILES: | CCN1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)N[C@@H]4CCCC[C@@H]4N |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CDK1 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CDK5, CDK7, SLK, SRC |
3 (equivalent to 1µM ≤ Kd < 10 µM) | EGFR, EIF2AK2 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20203 | CGP74514A KINOMEscan | KINOMEscan |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10355-101-1 | ||
| 10355-101-2 | EMD Millipore | D00170927 |
(Kd <100 nM)