Torkinib - Small Molecule (ID:10345-101)

HMS LINCS ID: 10345-101
Name: Torkinib
Alternative Names: PP242
LINCS ID: LSM-6357
PubChem CID: 57347681
ChEBI ID:
ChEMBL ID:
Molecular Mass: 308.14
InChi: InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,21,23H,1-2H3,(H2,17,18,19)
InChi Key: MTICIDWIKCANDD-UHFFFAOYSA-N
SMILES: CC(C)N1C2=C(C(=C3C=C4C=C(C=CC4=N3)O)N1)C(=NC=N2)N
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-08-17

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
MTOR

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20266
Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with nine kinase inhibitors
 Microscopy/Imaging
20267
Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors
 Microscopy/Imaging
20328
Torkinib KINOMEscan
 KINOMEscan

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10345-101-4 Selleck Chemicals
10345-101-5 Nathanael Gray (DFCI)