HG-14-10-04 - Small Molecule (ID:10342-101)

HMS LINCS ID: 10342-101
Name: HG-14-10-04
Alternative Names:
LINCS ID: LSM-6345
PubChem CID: 56655374
ChEBI ID:
ChEMBL ID:
Molecular Mass: 531.25
InChi: InChI=1S/C29H34ClN7O/c1-35-13-15-37(16-14-35)20-9-11-36(12-10-20)21-7-8-26(27(17-21)38-2)33-29-32-19-24(30)28(34-29)23-18-31-25-6-4-3-5-22(23)25/h3-8,17-20,31H,9-16H2,1-2H3,(H,32,33,34)
InChi Key: HRYNCLKDKCPYBF-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
ALK, CHEK1, CHEK2, CLK2, COQ8B, CSNK2A2, DYRK1A, EGFR, ERBB2, FER, FGFR1, FGFR4, FLT3, FLT4, INSR, INSRR, IRAK1, IRAK3, JAK2, JAK3, LTK, MAPK10, MAPK8, MAPK9, MERTK, MKNK2, MYO3B, PDGFRB, PLK4, PRKD2, PRKD3, PTK2, PTK2B, RET, ROS1, SLK, STK10, TSSK1B, ULK1, ULK3
10
(confirmed non-binding)
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Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20134
HG-14-10-04 KINOMEscan
 KINOMEscan

KINOMEscan Image

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10342-101-1 Nathanael Gray (DFCI) HG-14-10-04