HG-14-8-02 - Small Molecule (ID:10341-101)
| HMS LINCS ID: |
10341-101
|
| Name: | HG-14-8-02 |
| Alternative Names: | |
| LINCS ID: | LSM-6344 |
| PubChem CID: | 71496458 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 499.27 |
| InChi: | InChI=1S/C28H33N7O2/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32) |
| InChi Key: | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| SMILES: | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
EGFR, ERBB2, ERBB4, INSR, JAK3, MAP3K19 | |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20133 | HG-14-8-02 KINOMEscan | KINOMEscan |
KINOMEscan Image
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10341-101-1 | Nathanael Gray (DFCI) | HG-14-8-02 |
(equivalent to 100 nM ≤ Kd < 1µM)