Ipatasertib - Small Molecule (ID:10338-101)
| HMS LINCS ID: |
10338-101
|
| Name: | Ipatasertib |
| Alternative Names: | GDC 0068; GDC-0068; GDC0068; RG 7440; RG-7440; RG7440 |
| LINCS ID: | LSM-6341 |
| PubChem CID: | 24788740 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 457.22 |
| InChi: | InChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1 |
| InChi Key: | GRZXWCHAXNAUHY-NSISKUIASA-N |
| SMILES: | C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2017-05-09 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
AKT1, AKT2, AKT3, PRKG1 |
Batch Information for HMSL10338-101-2:
| HMS LINCS Batch ID: | 10338-101-2 |
| Provider: | MedChem Express |
| Provider Batch ID: | 08867 |
| Salt: | 101 |
| Molecular Formula: | C24H32ClN5O2 |
| Molecular Weight: | 458. |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-06-17 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10338-101-2:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10338-101-2_LCMS.pdf |
(Kd <100 nM)