Epigallocatechin gallate - Small Molecule (ID:10336-101)
| HMS LINCS ID: |
10336-101
|
| Name: | Epigallocatechin gallate |
| Alternative Names: | EGCG |
| LINCS ID: | LSM-5661 |
| PubChem CID: | 65064 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 458.08 |
| InChi: | InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1 |
| InChi Key: | WMBWREPUVVBILR-WIYYLYMNSA-N |
| SMILES: | C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ABCB1, APP, BCL2, DNMT1, Dyrk1a, mex-5, PGD, Sqle, STAT1, TDP1, ZWF1 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | BACE1, DYRK1A, MAPK14, MAPT, MET, MMP14, MMP2, pos-1, TERT |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10336-101-1 | Haoyuan chemexpress | HY-13653-20130101 |
(equivalent to 100 nM ≤ Kd < 1µM)