(+)-JQ1 - Small Molecule (ID:10328-101)
| HMS LINCS ID: |
10328-101
|
| Name: | (+)-JQ1 |
| Alternative Names: | (S)-JQ1 |
| LINCS ID: | LSM-6332 |
| PubChem CID: | 46907787 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 456.14 |
| InChi: | InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1 |
| InChi Key: | DNVXATUJJDPFDM-KRWDZBQOSA-N |
| SMILES: | CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
BRD2, BRD3, BRD4 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | BRDT |
10 (confirmed non-binding) |
Batch Information for HMSL10328-101-1:
| HMS LINCS Batch ID: | 10328-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HM-149_TM-20130205 |
| Salt: | 101 |
| Molecular Formula: | C23H25ClN4O2S |
| Molecular Weight: | 456.99 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2013-05-08 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10328-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10328-101-1_LCMS.pdf | |
| 05/13/2013 | PASS | None |
(Kd <100 nM)