Methylstat - Small Molecule (ID:10325-101)

HMS LINCS ID: 10325-101
Name: Methylstat
Alternative Names: luo2011_cmpd2
LINCS ID: LSM-43292
PubChem CID:
ChEBI ID:
ChEMBL ID:
Molecular Mass: 505.22
InChi: InChI=1S/C28H31N3O6/c1-36-27(33)16-15-26(32)31(35)18-5-4-17-29-19-21-11-13-22(14-12-21)20-37-28(34)30-25-10-6-8-23-7-2-3-9-24(23)25/h2-3,6-16,29,35H,4-5,17-20H2,1H3,(H,30,34)
InChi Key: MUJOCHRZXRZONW-UHFFFAOYSA-N
SMILES: COC(=O)C=CC(=O)N(CCCCNCC1=CC=C(C=C1)COC(=O)NC2=CC=CC3=CC=CC=C32)O
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2018-03-30

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
KDM4C

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20276
Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4)
 Microscopy/Imaging

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10325-101-1 Sigma-Aldrich 052M4604V