GSK-J1 - Small Molecule (ID:10321-110)
| HMS LINCS ID: |
10321-110
|
| Name: | GSK-J1 |
| Alternative Names: | |
| LINCS ID: | LSM-44939 |
| PubChem CID: | |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 388.18 |
| InChi: | InChI=1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)/p-1 |
| InChi Key: | AVZCPICCWKMZDT-UHFFFAOYSA-M |
| SMILES: | C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)[O-] |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
KDM6A, KDM6B |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10321-110-1 | Cayman Chemical | 0443776-3 |
(equivalent to 100 nM ≤ Kd < 1µM)