AGK2 - Small Molecule (ID:10317-101)
| HMS LINCS ID: |
10317-101
|
| Name: | AGK2 |
| Alternative Names: | |
| LINCS ID: | LSM-43196 |
| PubChem CID: | 1183107 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 433.04 |
| InChi: | InChI=1S/C23H13Cl2N3O2/c24-15-6-8-19(25)18(12-15)22-9-7-16(30-22)11-14(13-26)23(29)28-21-5-1-4-20-17(21)3-2-10-27-20/h1-12H,(H,28,29) |
| InChi Key: | SVENPFFEMUOOGK-UHFFFAOYSA-N |
| SMILES: | C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
SIRT2 | |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10317-101-1 | Cayman Chemical | 0444659-3 |
(equivalent to 100 nM ≤ Kd < 1µM)