Belinostat - Small Molecule (ID:10310-101)
| HMS LINCS ID: |
10310-101
|
| Name: | Belinostat |
| Alternative Names: | PXD101 |
| LINCS ID: | LSM-43181 |
| PubChem CID: | 53437714 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 318.07 |
| InChi: | InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18) |
| InChi Key: | NCNRHFGMJRPRSK-UHFFFAOYSA-N |
| SMILES: | C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC6, HDAC7, HDAC8 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | HDAC4, HDAC5, HDAC9 |
10 (confirmed non-binding) |
Batch Information for HMSL10310-101-1:
| HMS LINCS Batch ID: | 10310-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HY-10225-20111013 |
| Salt: | 101 |
| Molecular Formula: | C15H14N2O4S |
| Molecular Weight: | 318.35 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2013-05-08 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10310-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10310-101-1_LCMS.pdf | |
| 05/13/2013 | PASS | None |
(Kd <100 nM)