Garcinol - Small Molecule (ID:10307-101)
| HMS LINCS ID: |
10307-101
|
| Name: | Garcinol |
| Alternative Names: | |
| LINCS ID: | LSM-6319 |
| PubChem CID: | |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 602.36 |
| InChi: | InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-40,42H,7,13,15,18,20-21H2,1-6,8-10H3/t27-,28+,37+,38-/m0/s1 |
| InChi Key: | QDKLRKZQSOQWJQ-SMDXAGPFSA-N |
| SMILES: | CC([C@H](C/C=C(C)/C)C[C@]1(C[C@@H](C(C)=C)C/C=C(C)\C)C(O)=C2C(C3=CC(O)=C(O)C=C3)=O)(C)[C@](C/C=C(C)\C)(C1=O)C2=O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
EP300, KAT2B | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | GCN5, RTT109 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10307-101-1 | Cayman Chemical | 0441169-5 |
(equivalent to 100 nM ≤ Kd < 1µM)