JW55 - Small Molecule (ID:10305-101)
| HMS LINCS ID: |
10305-101
|
| Name: | JW55 |
| Alternative Names: | |
| LINCS ID: | LSM-6318 |
| PubChem CID: | 2946601 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 434.18 |
| InChi: | InChI=1S/C25H26N2O5/c1-30-21-10-6-19(7-11-21)25(12-15-31-16-13-25)17-26-23(28)18-4-8-20(9-5-18)27-24(29)22-3-2-14-32-22/h2-11,14H,12-13,15-17H2,1H3,(H,26,28)(H,27,29) |
| InChi Key: | ZJZWZIXSGNFWQQ-UHFFFAOYSA-N |
| SMILES: | COC1=CC=C(C=C1)C2(CCOCC2)CNC(=O)C3=CC=C(C=C3)NC(=O)C4=CC=CO4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
TNKS, TNKS2 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10305-101-1 | Tocris | 1A/136515 |
(equivalent to 100 nM ≤ Kd < 1µM)