RG-108 - Small Molecule (ID:10302-101)
| HMS LINCS ID: |
10302-101
|
| Name: | RG-108 |
| Alternative Names: | |
| LINCS ID: | LSM-6283 |
| PubChem CID: | 702558 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 334.10 |
| InChi: | InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1 |
| InChi Key: | HPTXLHAHLXOAKV-INIZCTEOSA-N |
| SMILES: | C1=CC=C2C(=C1)C(=O)N(C2=O)[C@@H](CC3=CNC4=CC=CC=C43)C(=O)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
DNMT1 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20276 | Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10302-101-1 | Haoyuan chemexpress | HY13642-20130408 |
(equivalent to 100 nM ≤ Kd < 1µM)