BMS-754807 - Small Molecule (ID:10290-101)
| HMS LINCS ID: |
10290-101
|
| Name: | BMS-754807 |
| Alternative Names: | |
| LINCS ID: | LSM-6218 |
| PubChem CID: | 24785538 |
| ChEBI ID: | |
| ChEMBL ID: | 575448 |
| Molecular Mass: | 461.21 |
| InChi: | InChI=1S/C23H24FN9O/c1-23(21(34)26-15-7-8-18(24)25-13-15)9-3-10-32(23)22-28-20(17-4-2-11-33(17)31-22)27-19-12-16(29-30-19)14-5-6-14/h2,4,7-8,11-14H,3,5-6,9-10H2,1H3,(H,26,34)(H2,27,28,29,30,31)/t23-/m0/s1 |
| InChi Key: | LQVXSNNAFNGRAH-QHCPKHFHSA-N |
| SMILES: | C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
Akt1, Igf1r, IGF1R | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | INSR |
3 (equivalent to 1µM ≤ Kd < 10 µM) | CCNE1, CCNE2, CDK2 |
10 (confirmed non-binding) |
Batch Information for HMSL10290-101-1:
| HMS LINCS Batch ID: | 10290-101-1 |
| Provider: | ChemieTek |
| Provider Batch ID: | CT-001 |
| Salt: | 101 |
| Molecular Formula: | C23H24FN9O |
| Molecular Weight: | 461.49 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2013-03-04 |
| Most Recent Update: | 2016-08-02 |
(Kd <100 nM)