SGI-1776 - Small Molecule (ID:10288-101)
| HMS LINCS ID: |
10288-101
|
| Name: | SGI-1776 |
| Alternative Names: | |
| LINCS ID: | LSM-6307 |
| PubChem CID: | 24795070 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 405.18 |
| InChi: | InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26) |
| InChi Key: | MHXGEROHKGDZGO-UHFFFAOYSA-N |
| SMILES: | CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
FLT3, GSG2, PIM1, PIM3 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | KCNH2, PIM2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | YES1 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10288-101-1 | Selleck Chemicals | S219802 |
(Kd <100 nM)