Vorinostat - Small Molecule (ID:10282-101)

HMS LINCS ID: 10282-101
Name: Vorinostat
Alternative Names: suberoylanilide hydroxamic acid (SAHA); Zolinza
LINCS ID: LSM-3828
PubChem CID: 5311
ChEBI ID:
ChEMBL ID:
Molecular Mass: 264.15
InChi: InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChi Key: WAEXFXRVDQXREF-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
HDAC6, LOC541932, NCOR1, NCOR2
2
(equivalent to 100 nM ≤ Kd < 1µM)
Hdac1, Hdac1, HDAC1, HDAC10, HDAC11, Hdac2, HDAC2, Hdac3, HDAC3, Hdac4, HDAC4, Hdac5, HDAC5, Hdac6, Hdac7, HDAC7, HDAC8, HDAC9
10
(confirmed non-binding)
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Batch Information for HMSL10282-101-3:

HMS LINCS Batch ID: 10282-101-3
Provider: MedChem Express
Provider Batch ID: 05628
Salt: 101
Molecular Formula: C14H20N2O3
Molecular Weight: 264.32
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-06-17
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10282-101-3:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10282-101-3_LCMS.pdf