SB-3CT - Small Molecule (ID:10274-101)
| HMS LINCS ID: |
10274-101
|
| Name: | SB-3CT |
| Alternative Names: | |
| LINCS ID: | LSM-4293 |
| PubChem CID: | 9883002 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 306.04 |
| InChi: | InChI=1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2 |
| InChi Key: | LSONWRHLFZYHIN-UHFFFAOYSA-N |
| SMILES: | C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MMP14, MMP2 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | MMP9 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | ADAM17 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
| 20270 | Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10274-101-1 | Enzo Life Sciences |
(Kd <100 nM)