PD 98059 - Small Molecule (ID:10271-101)
| HMS LINCS ID: |
10271-101
|
| Name: | PD 98059 |
| Alternative Names: | |
| LINCS ID: | LSM-3394 |
| PubChem CID: | 4713 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 267.09 |
| InChi: | InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3 |
| InChi Key: | QFWCYNPOPKQOKV-UHFFFAOYSA-N |
| SMILES: | COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MAP2K1, MAP2K2 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK1, MT-CO1, PTGS1, RAF1 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
| 20270 | Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10271-101-1 | Sigma-Aldrich | |
| 10271-101-2 | LC Laboratories |
(equivalent to 100 nM ≤ Kd < 1µM)