Glycyl-H-1152 - Small Molecule (ID:10253-102)
| HMS LINCS ID: |
10253-102
|
| Name: | Glycyl-H-1152 |
| Alternative Names: | |
| LINCS ID: | LSM-4274 |
| PubChem CID: | |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 376.16 |
| InChi: | InChI=1S/C18H24N4O3S/c1-13-7-8-20-15-5-3-6-16(18(13)15)26(24,25)22-10-4-9-21(12-14(22)2)17(23)11-19/h3,5-8,14H,4,9-12,19H2,1-2H3/t14-/m0/s1 |
| InChi Key: | SKZNXANHXFSDNA-AWEZNQCLSA-N |
| SMILES: | NCC(N(C[C@@H]1C)CCCN1S(C2=CC=CC3=NC=CC(C)=C32)(=O)=O)=O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-05-06 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ROCK2 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
| 20270 | Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10253-102-1 | Tocris |
(equivalent to 100 nM ≤ Kd < 1µM)