Etoposide - Small Molecule (ID:10250-101)
| HMS LINCS ID: |
10250-101
|
| Name: | Etoposide |
| Alternative Names: | |
| LINCS ID: | LSM-6348 |
| PubChem CID: | 36462 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 588.18 |
| InChi: | InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1 |
| InChi Key: | VJJPUSNTGOMMGY-MRVIYFEKSA-N |
| SMILES: | C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
TOP2A, TOP2B | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | ALOX15 |
10 (confirmed non-binding) |
Batch Information for HMSL10250-101-3:
| HMS LINCS Batch ID: | 10250-101-3 |
| Provider: | MedChem Express |
| Provider Batch ID: | 11793 |
| Salt: | 101 |
| Molecular Formula: | C29H32O13 |
| Molecular Weight: | 588.56 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2016-01-08 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10250-101-3:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 11/02/2015 | PASS | HMSL10250-101-3_LCMS.pdf |
(equivalent to 100 nM ≤ Kd < 1µM)