AG1024 - Small Molecule (ID:10239-101)
| HMS LINCS ID: |
10239-101
|
| Name: | AG1024 |
| Alternative Names: | Tyrphostin AG 1024 |
| LINCS ID: | LSM-4262 |
| PubChem CID: | 2044 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 304.02 |
| InChi: | InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3 |
| InChi Key: | ABBADGFSRBWENF-UHFFFAOYSA-N |
| SMILES: | CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
IGF1R |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
| 20270 | Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10239-101-1 | Calbiochem |
(equivalent to 100 nM ≤ Kd < 1µM)