GDC-0980 - Small Molecule (ID:10234-101)
| HMS LINCS ID: |
10234-101
|
| Name: | GDC-0980 |
| Alternative Names: | RG7422 |
| LINCS ID: | LSM-4257 |
| PubChem CID: | 66694608 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 498.22 |
| InChi: | InChI=1S/C23H30N8O3S/c1-14-17(13-29-3-5-31(6-4-29)22(33)15(2)32)35-19-18(14)27-20(16-11-25-23(24)26-12-16)28-21(19)30-7-9-34-10-8-30/h11-12,15,32H,3-10,13H2,1-2H3,(H2,24,25,26) |
| InChi Key: | YOVVNQKCSKSHKT-UHFFFAOYSA-N |
| SMILES: | CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)C(=O)C(C)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | FGR, MAP3K9, PIK3C2B, SYK |
3 (equivalent to 1µM ≤ Kd < 10 µM) | PIK3C2A, PIK3C3 |
10 (confirmed non-binding) |
Batch Information for HMSL10234-101-1:
| HMS LINCS Batch ID: | 10234-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HM-205_14-20120801 |
| Salt: | 101 |
| Molecular Formula: | C23H30N8O3S |
| Molecular Weight: | 498.6 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-11-14 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10234-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10234-101-1_LCMS.pdf |
(Kd <100 nM)