IKK16 - Small Molecule (ID:10228-102)
| HMS LINCS ID: |
10228-102
|
| Name: | IKK16 |
| Alternative Names: | |
| LINCS ID: | LSM-2309 |
| PubChem CID: | 9549298 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 483.21 |
| InChi: | InChI=1S/C28H29N5OS/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31) |
| InChi Key: | BWZJBXAPRCVCKQ-UHFFFAOYSA-N |
| SMILES: | C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
IKBKB | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | AURKA, AURKB, BRSK2, BTK, CAMK1, CDK2, CHEK1, CHUK, CLK2, CSK, CSNK2A1, CSNK2A2, CSNK2B, DAPK1, DYRK1A, DYRK2, DYRK3, EPHA2, EPHA4, EPHB1, EPHB2, EPHB3, EPHB4, FGFR1, FLT1, GCK, GSK3B, HIPK1, HIPK2, HIPK3, IGF1R, IKBKE, INSR, INSRR, JAK2, LCK, MAP2K1, MAP2K1, MAP3K11, MAP3K7, MAPK11, MAPK15, MAPK8, MARK3, MINK1, MKNK1, NTRK1, NUAK1, PAK5, PHKA2, PIM1, PIM3, PKD1, PKN2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKCA, PRKCA, RIPK2, ROCK2, RPS6KA1, RPS6KB1, SGK1, SRC, SRC, STK3, SYK, TAOK1, TBK1, YES1 |
10 (confirmed non-binding) |
Batch Information for HMSL10228-102-1:
| HMS LINCS Batch ID: | 10228-102-1 |
| Provider: | Tocris |
| Provider Batch ID: | reference date: Oct 2010 |
| Salt: | 102 |
| Molecular Formula: | C28H30ClN5OS |
| Molecular Weight: | 520.09 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-08-15 |
| Most Recent Update: | 2016-04-04 |
(Kd <100 nM)