EO1428 - Small Molecule (ID:10227-101)

HMS LINCS ID: 10227-101
Name: EO1428
Alternative Names:
LINCS ID: LSM-1228
PubChem CID: 9801969
ChEBI ID:
ChEMBL ID:
Molecular Mass: 414.01
InChi: InChI=1S/C20H16BrClN2O/c1-12-4-2-3-5-15(12)20(25)16-8-7-14(11-17(16)22)24-19-9-6-13(21)10-18(19)23/h2-11,24H,23H2,1H3
InChi Key: HDCLCHNAEZNGNV-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1C(=O)C2=C(C=C(C=C2)NC3=C(C=C(C=C3)Br)N)Cl
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
MAPK14
2
(equivalent to 100 nM ≤ Kd < 1µM)
MAPK11

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20233
Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors
 Bead-based immunoassay

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10227-101-1 Tocris reference date: Oct 2010
10227-101-2 Tocris