Dacomitinib - Small Molecule (ID:10222-101)
| HMS LINCS ID: |
10222-101
|
| Name: | Dacomitinib |
| Alternative Names: | PF-00299804 |
| LINCS ID: | LSM-42808 |
| PubChem CID: | 57519532 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 469.17 |
| InChi: | InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29) |
| InChi Key: | LVXJQMNHJWSHET-UHFFFAOYSA-N |
| SMILES: | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
EGFR, ERBB2, ERBB4 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10222-101-1 | Haoyuan chemexpress | HY-13272-20120208 |
(Kd <100 nM)