GSK2334470 - Small Molecule (ID:10221-101)

HMS LINCS ID: 10221-101
Name: GSK2334470
Alternative Names:
LINCS ID: LSM-1222
PubChem CID: 46215815
ChEBI ID:
ChEMBL ID:
Molecular Mass: 462.29
InChi: InChI=1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13,15,17-18H,3-9,14H2,1-2H3,(H,28,34)(H3,26,31,32)(H,27,29,30)/t15-,17+/m1/s1
InChi Key: QLPHOXTXAKOFMU-WBVHZDCISA-N
SMILES: C[C@@H]1CC[C@@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
PDK1, PDPK1
3
(equivalent to 1µM ≤ Kd < 10 µM)
AIM1, AURKB, ROCK1
10
(confirmed non-binding)
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Batch Information for HMSL10221-101-1:

HMS LINCS Batch ID: 10221-101-1
Provider: Tocris
Provider Batch ID:
Salt: 101
Molecular Formula: C25H34N8O
Molecular Weight: 462.59
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02

HMS QC Testing Events for HMSL10221-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10221-101-1_LCMS.pdf