KIN001-021 - Small Molecule (ID:10212-101)
| HMS LINCS ID: |
10212-101
|
| Name: | KIN001-021 |
| Alternative Names: | CGP082996; CINK4; ZINC01493715 |
| LINCS ID: | LSM-1213 |
| PubChem CID: | 24825971 |
| ChEBI ID: | |
| ChEMBL ID: | 1242367 |
| Molecular Mass: | 456.26 |
| InChi: | InChI=1S/C27H32N6O/c1-2-28-25-17-26(29-21-8-11-23(34)12-9-21)32-27(31-25)30-22-10-13-24-20(16-22)14-15-33(24)18-19-6-4-3-5-7-19/h3-7,10,13-17,21,23,34H,2,8-9,11-12,18H2,1H3,(H3,28,29,30,31,32) |
| InChi Key: | YVXCDLCJCIDFHE-UHFFFAOYSA-N |
| SMILES: | CCNC1=NC(=NC(=C1)NC2CCC(CC2)O)NC3=CC4=C(C=C3)N(C=C4)CC5=CC=CC=C5 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CDK4, EPHA3 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | CCND1, CDK6 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20225 | CGP082996 KINOMEscan | KINOMEscan |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10212-101-1 | Nathanael Gray (DFCI) |
(equivalent to 100 nM ≤ Kd < 1µM)