Go 6976 - Small Molecule (ID:10210-101)

HMS LINCS ID: 10210-101
Name: Go 6976
Alternative Names:
LINCS ID: LSM-1211
PubChem CID: 3501
ChEBI ID:
ChEMBL ID: 302449
Molecular Mass: 378.15
InChi: InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
InChi Key: VWVYILCFSYNJHF-UHFFFAOYSA-N
SMILES: CN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
AIM1, AURKA, AURKB, BLK, CDK1, CDK2, CDK5, CHEK2, EGFR, FLT3, GSK3A, GSK3B, IRAK4, ITK, JAK3, LIMK1, MAPK8, MARK2, MARK3, PAK4, PDK1, PDPK1, PKD1, PKD2, PLK4, PRKACA, Prkca, PRKCA, Prkcb, PRKCB, Prkcd, Prkce, Prkcg, PRKCG, Prkch, Prkcq, Prkcz, PRKD1, PRKD2, ROCK1, RPS6KA3, RPS6KB1, TYK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
ABL1, DYRK1A, ERBB2, FGFR1, FLG, FLT1, FLT4, FYN, JAK2, KDR, LYN, MAPK1, PIM1, PRKCD, ROCK2
3
(equivalent to 1µM ≤ Kd < 10 µM)
AKT1, AKT2, CAMK1, CHUK, CSF1R, CSNK1D, CSNK2A1, DAPK3, EPHA2, ERBB4, FGFR3, IGF1R, IKBKB, INSR, KIT, LCK, MAPK12, MAPK13, MAPK9, MAPKAPK2, MET, MYLK, PIM2, PLK1, PLK3, PRKCZ, PRKG1, SRC
10
(confirmed non-binding)
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Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10210-101-1 EMD Millipore EMD B64160 BIN: 65/0121404A1