BMS-536924 - Small Molecule (ID:10209-101)

HMS LINCS ID: 10209-101
Name: BMS-536924
Alternative Names: KIN001-126
LINCS ID: LSM-1210
PubChem CID: 68925359
ChEBI ID:
ChEMBL ID: 401930
Molecular Mass: 479.17
InChi: InChI=1S/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,28-30,32H,7-10,14H2,1H3/t21-/m1/s1
InChi Key: UGQMURPIMYALPH-OAQYLSRUSA-N
SMILES: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NC[C@H](C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
ALK, AXL, BLK, BMP2K, BTK, CDC42BPG, CSF1R, DAPK1, FGFR1, FGFR4, FLT3, FYN, HCK, IGF1R, INSR, INSRR, JAK1, JAK2, JAK3, KIT, LCK, LTK, MAP2K1, MAP2K2, MAP3K11, MAP3K9, MAP4K5, MERTK, NEK6, NTRK1, NTRK2, NTRK3, NUAK1, PAK5, PTK2, PTK2B, RET, RIOK1, ROS1, SRC, SRPK1, STK17A, STK17B, STK3, STK33, SYK, TIE1, TNIK, TNK1, TNK2, TYK2, ULK3
10
(confirmed non-binding)
(Click to show)

Batch Information for HMSL10209-101-1:

HMS LINCS Batch ID: 10209-101-1
Provider: Nathanael Gray (DFCI)/BMS
Provider Batch ID:
Salt: 101
Molecular Formula:
Molecular Weight:
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02