INK-128 - Small Molecule (ID:10205-101)
| HMS LINCS ID: |
10205-101
|
| Name: | INK-128 |
| Alternative Names: | MLN0128 |
| LINCS ID: | LSM-1206 |
| PubChem CID: | 45375953 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 309.13 |
| InChi: | InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19) |
| InChi Key: | GYLDXIAOMVERTK-UHFFFAOYSA-N |
| SMILES: | CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MTOR |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20343 | Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values | Microscopy/Imaging |
| 20344 | Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10205-101-1 | Haoyuan chemexpress | HY-13328-20120118 |
| 10205-101-2 | MedChem Express | 05351 |
(equivalent to 100 nM ≤ Kd < 1µM)