PF 573228 - Small Molecule (ID:10199-101)

HMS LINCS ID: 10199-101
Name: PF 573228
Alternative Names:
LINCS ID: LSM-1200
PubChem CID: 11612883
ChEBI ID:
ChEMBL ID:
Molecular Mass: 491.12
InChi: InChI=1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30)
InChi Key: HESLKTSGTIBHJU-UHFFFAOYSA-N
SMILES: CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
PTK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
CDK1, CDK7, Ptk2
3
(equivalent to 1µM ≤ Kd < 10 µM)
GSK3B, PTK2B

Batch Information for HMSL10199-101-1:

HMS LINCS Batch ID: 10199-101-1
Provider: Tocris
Provider Batch ID:
Salt: 101
Molecular Formula: C22H20F3N5O3S
Molecular Weight: 491.49
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02

HMS QC Testing Events for HMSL10199-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10199-101-1_LCMS.pdf
01/10/2012 PASS None