PF 573228 - Small Molecule (ID:10199-101)
| HMS LINCS ID: |
10199-101
|
| Name: | PF 573228 |
| Alternative Names: | |
| LINCS ID: | LSM-1200 |
| PubChem CID: | 11612883 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 491.12 |
| InChi: | InChI=1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30) |
| InChi Key: | HESLKTSGTIBHJU-UHFFFAOYSA-N |
| SMILES: | CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
PTK2 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CDK1, CDK7, Ptk2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | GSK3B, PTK2B |
Batch Information for HMSL10199-101-1:
| HMS LINCS Batch ID: | 10199-101-1 |
| Provider: | Tocris |
| Provider Batch ID: | |
| Salt: | 101 |
| Molecular Formula: | C22H20F3N5O3S |
| Molecular Weight: | 491.49 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-12-02 |
HMS QC Testing Events for HMSL10199-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10199-101-1_LCMS.pdf | |
| 01/10/2012 | PASS | None |
(Kd <100 nM)