Rigosertib - Small Molecule (ID:10184-110)
| HMS LINCS ID: |
10184-110
|
| Name: | Rigosertib |
| Alternative Names: | ON-01910 |
| LINCS ID: | LSM-44954 |
| PubChem CID: | |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 450.12 |
| InChi: | InChI=1S/C21H25NO8S/c1-27-15-10-19(29-3)16(20(11-15)30-4)7-8-31(25,26)13-14-5-6-18(28-2)17(9-14)22-12-21(23)24/h5-11,22H,12-13H2,1-4H3,(H,23,24)/p-1 |
| InChi Key: | OWBFCJROIKNMGD-UHFFFAOYSA-M |
| SMILES: | COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-] |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
PIK3CA, PIK3CB, PIK3CD, PIK3CG, PLK1 |
Batch Information for HMSL10184-110-2:
| HMS LINCS Batch ID: | 10184-110-2 |
| Provider: | MedChem Express |
| Provider Batch ID: | 10747 |
| Salt: | 110 |
| Molecular Formula: | C21H24NNaO8S |
| Molecular Weight: | 473.47 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-06-17 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10184-110-2:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10184-110-2_NMR.pdf, HMSL10184-110-2_LCMS.pdf |
(equivalent to 100 nM ≤ Kd < 1µM)