PF04217903 - Small Molecule (ID:10165-101)

HMS LINCS ID: 10165-101
Name: PF04217903
Alternative Names:
LINCS ID: LSM-1166
PubChem CID: 17754438
ChEBI ID:
ChEMBL ID:
Molecular Mass: 372.14
InChi: InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2
InChi Key: PDMUGYOXRHVNMO-UHFFFAOYSA-N
SMILES: C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
MET
3
(equivalent to 1µM ≤ Kd < 10 µM)
ABL1, ACVR1, AIM1, ALK, AURKA, AURKB, BTK, CAMK1D, CAMK2A, CDK5, CDK7, CDK8, CDK9, CHEK1, CLK2, CLK4, CSF1R, CSNK1A1, DAPK3, DYRK1A, DYRK1B, FGFR1, FLG, FLT1, FLT3, FYN, GRK5, GSK3A, GSK3B, IGF1R, IKBKE, JAK2, JAK3, KDR, LCK, LIMK1, LRRK2, LTK, MAP2K1, MAP2K2, MAP4K2, MAP4K4, MAPK14, MAPK8, MAPK9, MST1R, NEK2, NTRK1, NTRK2, NTRK3, PAK4, PDE10A, PDE3A, PDE3B, PDE5A, PDGFRA, PDGFRB, PIM1, PRKAA1, PRKACA, PRKCQ, PRKD3, PRKX, PTK2, RET, ROCK1, RPS6KA3, TAOK1, TBK1, TNK2, TYRO3
10
(confirmed non-binding)
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Batch Information for HMSL10165-101-1:

HMS LINCS Batch ID: 10165-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-12017_1-20091026
Salt: 101
Molecular Formula: C19H16N8O
Molecular Weight: 372.38
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10165-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10165-101-1_LCMS.pdf
11/14/2011 PASS None