Olaparib - Small Molecule (ID:10144-101)
| HMS LINCS ID: |
10144-101
|
| Name: | Olaparib |
| Alternative Names: | AZD2281; KU-0059436 |
| LINCS ID: | LSM-1145 |
| PubChem CID: | 23725625 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 434.18 |
| InChi: | InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30) |
| InChi Key: | FDLYAMZZIXQODN-UHFFFAOYSA-N |
| SMILES: | C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
PARP1, PARP2 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | TNKS |
Batch Information for HMSL10144-101-1:
| HMS LINCS Batch ID: | 10144-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HM-042_8-20100517 |
| Salt: | 101 |
| Molecular Formula: | C24H23FN4O3 |
| Molecular Weight: | 434.46 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10144-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 11/14/2011 | PASS | None |
(Kd <100 nM)