BMS 777607 - Small Molecule (ID:10143-101)

HMS LINCS ID: 10143-101
Name: BMS 777607
Alternative Names:
LINCS ID: LSM-1144
PubChem CID: 24794418
ChEBI ID:
ChEMBL ID:
Molecular Mass: 512.11
InChi: InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
InChi Key: VNBRGSXVFBYQNN-UHFFFAOYSA-N
SMILES: CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
AIM1, AURKB, AXL, FLT3, MERTK, MET, MST1R, TYRO3
2
(equivalent to 100 nM ≤ Kd < 1µM)
BLK, EPHA3, KDR, KIT, LCK, MKNK2, MUSK, NTRK1, NTRK2, PDGFRB, SRC, STK10, TEK
3
(equivalent to 1µM ≤ Kd < 10 µM)
BTK, CHUK, EGFR, FCGR1A, GSK3B, INSR, JAK2, MAPK14, MAPKAPK2, PIM1, PLK1

Batch Information for HMSL10143-101-1:

HMS LINCS Batch ID: 10143-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-12076-20110602
Salt: 101
Molecular Formula: C25H19ClF2N4O4
Molecular Weight: 512.89
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10143-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10143-101-1_LCMS.pdf
11/14/2011 PASS None