Momelotinib - Small Molecule (ID:10140-101)
HMS LINCS ID: | 10140-101 |
Name: | Momelotinib |
Alternative Names: | CYT387 |
LINCS ID: | LSM-1141 |
PubChem CID: | 25062766 |
ChEBI ID: | |
ChEMBL ID: | |
Molecular Mass: | 414.18 |
InChi: | InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28) |
InChi Key: | ZVHNDZWQTBEVRY-UHFFFAOYSA-N |
SMILES: | C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N |
Relevant Citations: | |
Comments: | |
Date Publicly Available: | |
Most Recent Update: | 2016-07-12 |
Target Affinity:
(see Study 20000)Target Affinity Spectrum Value | HUGO Gene Name |
---|---|
JAK1, JAK2 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CHUK, JAK3, MYLK4, RIOK3 |
10 (confirmed non-binding) |
Batch Information for HMSL10140-101-1:
HMS LINCS Batch ID: | 10140-101-1 |
Provider: | Haoyuan chemexpress |
Provider Batch ID: | HM-075_9-20110304 |
Salt: | 101 |
Molecular Formula: | C23H22N6O2 |
Molecular Weight: | 414.46 |
Purity: | |
Purification Method: | |
Chemical Synthesis Reference: | |
Comments: | |
Date Publicly Available: | 2011-07-15 |
Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10140-101-1:
Date | HMS QC Outcome | Comment | Files |
---|---|---|---|
04/13/2015 | PASS | HMSL10140-101-1_LCMS.pdf | |
11/14/2011 | PASS | None |
(Kd <100 nM)