AZD-1480 - Small Molecule (ID:10139-101)
| HMS LINCS ID: |
10139-101
|
| Name: | AZD-1480 |
| Alternative Names: | |
| LINCS ID: | LSM-1140 |
| PubChem CID: | 46861588 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 348.10 |
| InChi: | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24) |
| InChi Key: | PDOQBOJDRPLBQU-UHFFFAOYSA-N |
| SMILES: | CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
JAK2, NTRK1, STAT3, STAT5A | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | JAK3 |
Batch Information for HMSL10139-101-1:
| HMS LINCS Batch ID: | 10139-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HM-060_10-20110418 |
| Salt: | 101 |
| Molecular Formula: | C14H14ClFN8 |
| Molecular Weight: | 348.77 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10139-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10139-101-1_LCMS.pdf | |
| 11/14/2011 | PASS | None |
(Kd <100 nM)