TPCA-1 - Small Molecule (ID:10136-101)

HMS LINCS ID: 10136-101
Name: TPCA-1
Alternative Names:
LINCS ID: LSM-1136
PubChem CID: 9903786
ChEBI ID:
ChEMBL ID:
Molecular Mass: 279.05
InChi: InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
InChi Key: SAYGKHKXGCPTLX-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
IKBKB, JAK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
AURKA, AURKB, BRSK1, BTK, CDK2, CHEK2, DAPK1, EIF2AK2, EPHA4, EPHB1, EPHB2, EPHB3, ERBB4, FGFR1, FLT1, GCK, IGF1R, IKBKE, IRAK4, MAP2K1, MAP2K1, MAP2K2, MAP3K1, MAP3K11, MAP3K7, MAP3K9, MAPK15, MINK1, NTRK1, NUAK1, PRKAA1, PRKAA2, PRKAB1, PRKAB2, RIPK2, RPS6KA1, SRC, SRC, STK26, STK3, TAOK1, YES1
10
(confirmed non-binding)
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Batch Information for HMSL10136-101-1:

HMS LINCS Batch ID: 10136-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HM-093_6-20110128
Salt: 101
Molecular Formula: C12H10FN3O2S
Molecular Weight: 279.29
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10136-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10136-101-1_LCMS.pdf
11/14/2011 PASS None