GSK1904529A - Small Molecule (ID:10134-101)

HMS LINCS ID: 10134-101
Name: GSK1904529A
Alternative Names:
LINCS ID: LSM-1134
PubChem CID: 25124816
ChEBI ID:
ChEMBL ID: 466397
Molecular Mass: 851.34
InChi: InChI=1S/C44H47F2N9O5S/c1-5-28-26-35(38(60-3)27-36(28)53-19-15-30(16-20-53)52-21-23-54(24-22-52)61(4,57)58)49-44-47-17-14-34(48-44)42-40(50-39-11-6-7-18-55(39)42)29-12-13-37(59-2)31(25-29)43(56)51-41-32(45)9-8-10-33(41)46/h6-14,17-18,25-27,30H,5,15-16,19-24H2,1-4H3,(H,51,56)(H,47,48,49)
InChi Key: MOSKATHMXWSZTQ-UHFFFAOYSA-N
SMILES: CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
IGF1R, INSR
3
(equivalent to 1µM ≤ Kd < 10 µM)
AIM1, AURKA, AURKB, LCK
10
(confirmed non-binding)
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Batch Information for HMSL10134-101-3:

HMS LINCS Batch ID: 10134-101-3
Provider: MedChem Express
Provider Batch ID: 03710
Salt: 101
Molecular Formula: C44H47F2N9O5S
Molecular Weight: 851.96
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-06-17
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10134-101-3:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10134-101-3_LCMS.pdf